医学
概化理论
随机对照试验
背景(考古学)
心理干预
干预(咨询)
物理医学与康复
忽视
冲程(发动机)
物理疗法
精神科
心理学
发展心理学
病理
古生物学
机械工程
工程类
生物
作者
Alexandra Zezinka Durfee,Argye E. Hillis
出处
期刊:Stroke
[Ovid Technologies (Wolters Kluwer)]
日期:2023-01-01
卷期号:54 (1): 10-19
被引量:6
标识
DOI:10.1161/strokeaha.122.041710
摘要
Unilateral spatial neglect (USN) is a common and disabling cognitive consequence of stroke wherein individuals demonstrate decreased response to contralesional information. Here, we provide an updated narrative review of studies that shed light on the neural mechanisms and predictors of recovery of USN. Additionally, we report a rapid review of randomized controlled trials focusing on USN intervention, both nonpharmacological and pharmacological, published in the last 5 years. Randomized controlled trials are reviewed within the context of systematic reviews and meta-analyses of USN interventions published within the same time frame. The quality of randomized controlled trials of treatment is higher compared to quality reported in previous reviews and meta-analyses. However, remaining weaknesses in participant demographic reporting, as well as small, heterogenous samples, render generalizability and cross-study interpretation a challenge. Nevertheless, evidence regarding neural mechanisms underlying USN recovery and regarding the effectiveness of targeted USN interventions is accumulating and strengthening, setting the foundation for future investigations into patient-specific factors that may influence treatment response. We identify gaps and provide suggestions for future USN intervention research.
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