急性呼吸窘迫综合征
自噬
巨噬细胞
医学
肺泡巨噬细胞
急性呼吸窘迫
炎症
免疫学
肺
生物
内科学
细胞凋亡
生物化学
体外
作者
Chang Liu,Kun Xiao,Lixin Xie
标识
DOI:10.3389/fimmu.2022.922702
摘要
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a critical clinical syndrome with high morbidity and mortality that poses a major challenge in critical care medicine. The development of ALI/ARDS involves excessive inflammatory response, and macrophage autophagy plays an important role in regulating the inflammatory response in ALI/ARDS. In this paper, we review the effects of autophagy in regulating macrophage function, discuss the roles of macrophage autophagy in ALI/ARDS, and highlight drugs and other interventions that can modulate macrophage autophagy in ALI/ARDS to improve the understanding of the mechanism of macrophage autophagy in ALI/ARDS and provide new ideas and further research directions for the treatment of ALI/ARDS.
科研通智能强力驱动
Strongly Powered by AbleSci AI