Electrical heating fabrics that possess the excellent characteristics of lightweight, soft, and rapid heating were exploited to address the warmth problem in the cold winter. In this study, a stretchable and effective graphene-decorated weft-knitted fabric heater was developed by spray-drying approach. The graphene-decorated weft-knitted fabric has good stretchability with the strain of 124%, and a high thermal response that reached 206°C with voltage of 10 V. The heating performance of the graphene-decorated weft-knitted fabric remained unchanged at 20 cycles. Furthermore, a three-dimensional geometric model of graphene-decorated weft-knitted fabric was constructed. Mathematical modeling and visual simulation analysis were carried out to explore the electro-thermal coupling behavior. The electro-thermal conversion simulation results are basically consistent with the experimental data. The results offer an approach to design flexible and wearable electrical heating fabrics for thermal management.