作者
Makoto YAMAGISHI,Yuta Kuze,Seiichiro Kobayashi,Makoto Nakashima,Satoko Morishima,Toyotaka Kawamata,Junya Makiyama,Kako Suzuki,Masahide Seki,Kazumi Abe,Kiyomi Imamura,Eri Watanabe,Kazumi Tsuchiya,Isao Yasumatsu,Gensuke Takayama,Yoshiyuki Hizukuri,Kazumi Ito,Yukihiro Taira,Yasuhito Nannya,Arinobu Tojo,Toshiki Watanabe,Shinji Tsutsumi,Yutaka Suzuki,Kaoru Uchimaru
摘要
Epigenomes enable the rectification of disordered cancer gene expression, thereby providing new targets for pharmacological interventions. The clinical utility of targeting histone H3 lysine trimethylation (H3K27me3) as an epigenetic hallmark has been demonstrated