RUNX3 alleviates mitochondrial dysfunction and tubular damage by inhibiting TLR4/NF‐κB signalling pathway in diabetic kidney disease

The impaired function of tubular mitochondria is critical in diabetic kidney disease (DKD) progression. RUNX3 is down-regulated in DKD models. We intend to explore the effects of RUNX3 on mitochondrial dysfunction and renal tubule injury in DKD and related mechanisms.