材料科学
钛
骨整合
氮化硅
氮化钛
硅
纳米技术
光电子学
氮化物
植入
冶金
医学
外科
图层(电子)
作者
Zhiquan Huang,Heyang Zhou,Yuan Fang,Jin Wu,Shanshan Yuan,Kunzhan Cai,Xiao Tao,Xiyu Zhang,Chunbo Tang,Jian Chen
出处
期刊:ACS Biomaterials Science & Engineering
[American Chemical Society]
日期:2024-05-15
卷期号:10 (6): 4059-4072
标识
DOI:10.1021/acsbiomaterials.4c00427
摘要
The silicon nitride (Si3N4) coating exhibits promising potential in oral applications due to its excellent osteogenic and antibacterial properties. However, a comprehensive investigation of Si3N4 coatings in the context of dental implants is still lacking, especially regarding their corrosion resistance and in vivo performance. In this study, Si3N4 coatings were prepared on a titanium surface using the nonequilibrium magnetron sputtering method. A systematic comparison among the titanium group (Ti), Si3N4 coating group (Si3N4–Ti), and sandblasted and acid-etched-treated titanium group (SLA-Ti) has been conducted in vitro and in vivo. The results showed that the Si3N4–Ti group had the best corrosion resistance and antibacterial properties, which were mainly attributed to the dense structure and chemical activity of Si–O and Si–N bonds on the surface. Furthermore, the Si3N4–Ti group exhibited superior cellular responses in vitro and new bone regeneration and osseointegration in vivo, respectively. In this sense, silicon nitride coating shows promising prospects in the field of dental implantology.
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