Examining the vinyl moiety as a protecting group for hydroxyl (–OH) functionality under basic conditions
化学
部分
保护组
有机化学
组合化学
群(周期表)
烷基
作者
Vladimir V. Voronin,Maria S. Ledovskaya,Konstantin S. Rodygin,Valentine P. Ananikov
出处
期刊:Organic chemistry frontiers [The Royal Society of Chemistry] 日期:2020-01-01卷期号:7 (11): 1334-1342被引量:30
标识
DOI:10.1039/d0qo00202j
摘要
A method for the protection and deprotection of alcohols via vinylation and devinylation reactions is proposed. Stability of the vinyl protecting group under various conditions is studied and synthetic applicability is demonstrated.