Association of habitual alcohol consumption with carotid atherosclerotic lesions: results from the Corinthia study

医学 饮酒量 内科学 葡萄酒 内膜中层厚度 心脏病学 酒精摄入量 颈动脉 胃肠病学 食品科学 生物化学 化学
作者
Panagiotis Theofilis,Evangelos Oikonomou,Georgia Vogiatzi,George Lazaros,Sotirios Tsalamandris,Vasiliki Chara Mystakidi,Athina Goliopoulou,Christos Chasikidis,Antigoni Miliou,Petros Fountoulakis,Νικόλαος Παπαϊωάννου,M Papakonstantinou,Dimitris Tousoulis
出处
期刊:European Heart Journal [Oxford University Press]
卷期号:41 (Supplement_2) 被引量:1
标识
DOI:10.1093/ehjci/ehaa946.2863
摘要

Abstract Introduction Alcohol is implicated in the pathophysiology of cardiovascular diseases. However, it is also believed to play a cardioprotective role if consumed in appropriate amounts. Purpose To assess the association between alcohol consumption and carotid atherosclerosis. Methods In the setting of the cross-sectional Corinthia study, volunteers filled in questionnaires regarding drinking habits and were characterized as social drinkers (SD) or habitual alcohol consumers (HAC). Furthermore, they underwent carotid ultrasonography examination to evaluate the carotid intima-media thickness (cIMT). Thickness of cIMT>1.5 mm or protrusion >50% compared to adjacent segments was considered as atherosclerotic plaque. Results HAC consumers were usually male (HAC: 61.1%, SD: 24.9%, p<0.001), smokers (HAC: 33.3%, SD: 23.5%, p<0.001) and frequently had a history of hypertension (HAC: 72.8%, SD: 67.5%, p=0.02) when compared to SD (Table 1). However, no significant differences were noted regarding other risk factors of atherosclerosis (Table). Notably, HAC had a greater extent of carotid atherosclerosis as demonstrated by an increased cIMT (HAC: 1.03±0.45mm, SD: 0.96±0.39mm, p<0.001) and carotid plaque burden (HAC: 27.7%, SD: 21.3%, p=0.004). Importantly, when taking into account the number of alcoholic drinks (in wine glasses), alcohol consumption of more than 1 wine glass resulted in significantly higher values of cIMT (1 wine glass: 1.00±0.42mm, >1 wine glass: 1.06±0.45mm, p=0.04) (Figure 1A) and extensive amount of carotid plaques (1 wine glass: 22.7%, >1 wine glass: 30.4%, p=0.02) when compared to consumption of 1 wine glass (Figure 1B). Conclusion Habitual alcohol consumption of more than one wine glass is associated with a higher carotid atherosclerotic burden. Figure 1 Funding Acknowledgement Type of funding source: None
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
跳跃曼文发布了新的文献求助10
刚刚
瓜子发布了新的文献求助10
1秒前
ddddddd完成签到 ,获得积分10
3秒前
5秒前
沐夕完成签到,获得积分10
8秒前
fd发布了新的文献求助10
10秒前
10秒前
王小妍的王完成签到,获得积分10
11秒前
可爱的石头完成签到,获得积分10
13秒前
啦啦啦发布了新的文献求助10
15秒前
花非花雾非雾完成签到,获得积分10
17秒前
在水一方应助逸风望采纳,获得10
17秒前
充电宝应助打我呀采纳,获得10
17秒前
JYQ发布了新的文献求助20
18秒前
19秒前
20秒前
22秒前
24秒前
雪白不斜发布了新的文献求助10
26秒前
liangxianli发布了新的文献求助10
26秒前
Yang发布了新的文献求助10
29秒前
30秒前
shuangfeng1853完成签到 ,获得积分10
32秒前
zxq1996完成签到 ,获得积分10
33秒前
井野浮应助葵葵采纳,获得10
34秒前
34秒前
35秒前
Yang完成签到,获得积分10
35秒前
Hello应助两颗西柚采纳,获得10
36秒前
36秒前
37秒前
fortune发布了新的文献求助10
37秒前
douyq发布了新的文献求助10
39秒前
39秒前
大方乘云发布了新的文献求助10
40秒前
斯文败类应助6_6采纳,获得10
41秒前
41秒前
yuuuu01发布了新的文献求助10
43秒前
43秒前
周杰伦发布了新的文献求助10
44秒前
高分求助中
歯科矯正学 第7版(或第5版) 1004
SIS-ISO/IEC TS 27100:2024 Information technology — Cybersecurity — Overview and concepts (ISO/IEC TS 27100:2020, IDT)(Swedish Standard) 1000
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
Semiconductor Process Reliability in Practice 720
GROUP-THEORY AND POLARIZATION ALGEBRA 500
Mesopotamian divination texts : conversing with the gods : sources from the first millennium BCE 500
Days of Transition. The Parsi Death Rituals(2011) 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3233052
求助须知:如何正确求助?哪些是违规求助? 2879715
关于积分的说明 8212369
捐赠科研通 2547202
什么是DOI,文献DOI怎么找? 1376619
科研通“疑难数据库(出版商)”最低求助积分说明 647677
邀请新用户注册赠送积分活动 623067