化学
吡咯烷
哌啶
吗啉
氮丙啶
催化作用
组合化学
表面改性
分子
有机化学
纳米技术
材料科学
戒指(化学)
物理化学
作者
Sebastian Engl,Oliver Reiser
出处
期刊:Organic Letters
[American Chemical Society]
日期:2021-07-01
卷期号:23 (14): 5581-5586
被引量:33
标识
DOI:10.1021/acs.orglett.1c02035
摘要
Herein we report a catalyst- and metal-free visible-light-mediated protocol enabling the iodoamination of miscellaneous olefins. This protocol is characterized by high yields under environmentally benign reaction conditions utilizing commercially available substrates and a green and biodegradable solvent. Furthermore, the protocol allows for late-stage functionalization of bioactive molecules and can be scaled to gram quantities of product, which offers manifold possibilities for further transformations, including morpholine, piperidine, pyrrolidine, and aziridine synthesis.
科研通智能强力驱动
Strongly Powered by AbleSci AI