Cytologic Investigations for the Diagnosis of Malignant Pleural Effusion in Non–small Cell Lung Cancer

医学 肺癌 胸腔积液 恶性胸腔积液 细胞学 癌症 疾病 放射科 医学诊断 渗出 病理 内科学 外科
作者
Samira Shojaee,Sinchita Roy‐Chowdhuri,J. Safi,Horiana B. Grosu
出处
期刊:Journal of bronchology & interventional pulmonology 卷期号:28 (4): 310-321 被引量:9
标识
DOI:10.1097/lbr.0000000000000789
摘要

Lung cancer is the current leading cause of cancer-related deaths worldwide, and malignant pleural effusion, an indicator of the advanced stage of this disease, portends a poor prognosis. Thus, making an accurate diagnosis of malignant pleural effusion is of paramount importance. During the past decade, the prognosis of patients with advanced non-small cell lung cancer has improved substantially, especially in those treated with targeted therapy and immunotherapy. The use of pleural fluid cytology should not only provide diagnoses but also aid in the selection of targeted therapies, especially when obtaining a histologic specimen is too difficult. In this evidence-based review, we address the importance of pleural fluid cytology in non-small cell lung cancer patients, from making the diagnosis to making treatment-related decisions when only pleural fluid is available.

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