Biomimetic Mineralization of Prussian Blue Analogue-Incorporated Glucose Oxidase Hybrid Catalyst for Glucose Detection

A copper analogue of Prussian blue incorporated multienzyme system was successfully established via a biomimetic mineralization process, whereas CPB with peroxidase-like activity provided protecting effect for encapsulated glucose oxidase from attack in hostile conditions. The hybrid composite was developed as a colorimetric biosensor for ultrasensitive detection of glucose, with a low detection limit (0.48 μM).