Location of infarcts and post-stroke cognitive impairment

Historically, disability after a stroke has been mainly considered a matter of motor impairment. This notion has been reflected in an incomplete appreciation among physicians of its other consequences. For example, only two out of 15 items of the National Institutes of Health stroke scale, the most commonly used scale in the acute stroke setting, assess cognition. Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohortsTo the best of our knowledge, this study provides the first comprehensive map of strategic infarct locations associated with risk of PSCI. A location impact score was derived from this map that robustly predicted PSCI across cohorts. Furthermore, we developed a quick and reliable visual rating scale that might in the future be applied by clinicians to identify individual patients at risk of PSCI. Full-Text PDF