A surface-imprinted surface-enhanced Raman scattering sensor for histamine detection based on dual semiconductors and Ag nanoparticles

A highly sensitive molecularly imprinted surface-enhanced Raman scattering (SERS) sensor was developed for selective detection of histamine. A combination of two semiconductors and Ag nanoparticles (NPs) was used as the SERS substrate. The SERS was induced by Ag NPs plasmon resonances as well as charge-transfer between the semiconductors and the Ag NPs. The Raman intensity and the logarithm of the histamine concentration were linear over the range 10-8-10-3 mol L-1. The sensor exhibited good selectivity and had a sensitivity limit of 3.088 × 10-9 mol L-1. Histamine was detected in a spiked liquor sample, and its recoveries were in the range of 89.89%-109.18%.