Vicinal Trifluoromethylthioamination of Alkenes with Trifluoromethanesulfenamides

Abstract A general and efficient vicinal trifluoromethylthioamination of alkenes has been accomplished at room temperature in the presence of BF 3 ⋅ OEt 2 using trifluoromethanesulfenamides. Diversely substituted trifluoromethylthiolated amine derivatives were achieved in good yields in a single step. Importantly, trifluoromethanesulfenamides play dual role as ‘SCF 3 ’ and amine source, which allows high atom‐efficient approach to access 1‐trifluoromethylthio‐2‐aminoalkane derivatives.