子序列
基因组
最长公共子序列
递增子序列
基因
组合数学
基因家族
计算机科学
生物
计算生物学
遗传学
数学
有界函数
数学分析
作者
Shutao Zhang,Ruizhi Wang,Daming Zhu,Haitao Jiang,Haodi Feng,Jiong Guo,Xiaowen Liu
标识
DOI:10.1109/bibm.2018.8621304
摘要
In this paper, we propose to find order conserved subsequences of genomes by finding longest common exemplar subsequences of the genomes. The longest common exemplar subsequence problem is given by two genomes, asks to find a common exemplar subsequence of them, such that the exemplar subsequence length is maximized. We focus on genomes whose genes of the same gene family are in at most s spans. We propose a dynamic programming algorithm with time complexity O(s4 s mn) to find a longest common exemplar subsequence of two genomes with one genome admitting s span genes of the same gene family, where m, n stand for the gene numbers of those two given genomes. Our algorithm can be extended to find longest common exemplar subsequences of more than one genomes.
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