内皮功能障碍
内皮
发病机制
医学
血管舒缩
生物信息学
生物
免疫学
心脏病学
内科学
作者
Л. В. Васина,Н. Н. Петрищев,Т. Д. Власов
出处
期刊:Regionarnoe krovoobraŝenie i mikrocirkulâciâ
[FSBEI HE I.P. Pavlov SPbSMU MOH Russia]
日期:2017-03-30
卷期号:16 (1): 4-15
被引量:48
标识
DOI:10.24884/1682-6655-2017-16-1-4-15
摘要
Endothelial dysfunction is considered as a universal non-specific link in the pathogenesis of many diseases, primarily the cardiovascular system. This review is devoted to the discussion of the main functions of the endothelium and mechanisms for their implementation. One of the most striking features of endothelial cells is their morphological heterogeneity, which allows us to identify several typical forms of endothelial dysfunction (vasomotor, hemostatic, adhesion and angiogenous). Also, the review presents the most promising predictors of cardiovascular diseases and their complications among endothelial damage markers.
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