To investigate the CO2 corrosion of tubing in CO2 injection for production wells, the corrosion process is divided into four stages. Then the corrosive components, liquid production, water cut, wellhead temperature and production pressure difference at each stage are obtained. Based on these and in consideration of the changes in parameters, the prediction method for corrosion rate of tubing in CO2 flooding well is studied. Finally, the corrosion rate of the tubing in the example well at different stages is predicted and compared with the measured results.