医学
蛛网膜下腔出血
改良兰金量表
腰椎
荟萃分析
外科
麻醉
室外引流
腰椎穿刺
血管痉挛
入射(几何)
脑脊液
内科学
脑积水
缺血性中风
缺血
物理
光学
作者
M. Maher Hulou,Muhammed Amir Essibayi,Arnau Benet,Michael T. Lawton
标识
DOI:10.1016/j.wneu.2022.07.061
摘要
This study reviews the use of lumbar drains (LDs) after aneurysmal subarachnoid hemorrhage (aSAH) and compares the outcomes to those associated with external ventricular drains (EVDs) and controls. A comprehensive search of the literature was performed. English language studies with a sample size of more than 10 patients were included. One-arm and 2-arm meta-analyses were designed to compare external drainage groups. Random-effects models, heterogeneity measures, and risk of bias were calculated. Seventeen studies were included in the meta-analysis. The 2-arm meta-analysis comparing the LD to no drainage after aSAH found a significant improvement in the postoperative modified Rankin Scale (mRS) score (0–2) within 1 month of hospital discharge in the LD group (P = 0.003), a lower mortality rate (P = 0.03), fewer cases of clinical vasospasm (P = 0.007), and a lower incidence of ischemic stroke or delayed ischemic neurological deficits (P = 0.003). When the LD was compared to EVDs, a significant improvement in the postoperative mRS score (0–2) within 1 month of discharge was found in the LD group (P < 0.001). In the LD group, rebleeding occurred in 15 (3.4%) cases and meningitis occurred in 50 (4.7%) cases. Compared with patients without cerebrospinal fluid drainage, patients with the LD after aSAH had lower mortality rates, lower risk of clinical vasospasm, and lower risk of ischemic stroke, and they were more likely to have an mRS score of 0–2 within 1 month of discharge. Compared with patients with EVDs, patients with the LD were more likely to have an mRS score of 0–2 within 1 month of discharge.
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