多不饱和脂肪酸
生物化学
生物合成
碳链
细菌
脂肪酸
长链
无脊椎动物
化学
生物
有机化学
基因
生态学
遗传学
高分子科学
作者
Lucie Kyselová,Milada Vítová,Tomáš Řezanka
标识
DOI:10.1016/j.plipres.2022.101180
摘要
Very long chain fatty acids (VLCFAs) are important components of various lipid classes in most organisms, from bacteria to higher plants and mammals, including humans. VLCFAs, or very long chain polyunsaturated fatty acids (VLCPUFAs), can be defined as fatty acids with 23 or more carbon atoms in the molecule. The main emphasis in this review is on the analysis of these acids, including obtaining standards from natural sources or their synthesis. Furthermore, the occurrence and analysis of these compounds in both lower (bacteria, invertebrates) and higher organisms (flowering plants or mammals) are discussed in detail. Attention is paid to their biosynthesis, especially the elongation of very long chain fatty acids protein (ELOVL4). This review deals with papers describing these very interesting compounds, whose chemical, biochemical and biological properties have not been fully explored.
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