SO 2 F 2 ‐Promoted Dehydroxylative Fluorination of Alcohols

Abstract Reported here is the development of a novel, mild and practical protocol for the SO 2 F 2 ‐promoted dehydroxylative fluorination of readily available alcohols. The advantages of this protocol include an inexpensive and available reagent, and operational simplicity. This method enables the transformation of many kinds of primary, secondary and tertiary (hetero) arene alcohols into the corresponding fluorides and tolerates a range of functional groups. And the reactions occur smoothly to give the desired products in moderate to high yields. And a tentative mechanism was proposed involving formation and elimination of key intermediate, sulfonyl ester.