Simultaneous resolution of serotonin and epinephrine at poly (Victoria blue B) amplified carbon paste electrode: A voltammetric study with density functional theory evidences

• P-VBB/MCPE was formulated through electrochemical procedure. • Enhanced electrocatalytic behaviour was noticed at modified electrode. • Simultaneous analysis of 5-HT and EP was carried out using voltammetry. • Low detection limit was achieved. Herein, a polymerised film of Victoria blue B monomer was deposited on carbon paste electrode surface and characterised by using scanning electron microscope and electrochemical methods. The polymer film amplified electrode exemplified the elevated electrocatalytic oxidation of 5-HT and EP in presence 0.2 M PBS of physiological pH. The various experimental settings such as effect of supporting electrolyte, scan rate and varying the concentration of targeted analytes were scrutinized and the designed sensor depicts the lower detection limit for 5-HT (0.89 μM) and EP(0.33 μM). The proposed modified electrode also implemented for concurrent resolution and determination of serotonin (5-HT) and epinephrine (EP) by cyclic and differential pulse voltammetry also shows satisfactory steadiness towards 5-HT and EP.