A Short Review on Glucogallin and its Pharmacological Activities

保健品 天然产物 多酚 抗氧化剂 药理学 传统医学 医学 化学 生物化学
作者
Dipanjan Ghosh,Anam Najib Khan,Rajveer Singh,Arka Bhattacharya,Rudra Chakravarti,Syamal Roy,V. Ravichandiran
出处
期刊:Mini-reviews in Medicinal Chemistry [Bentham Science]
卷期号:22 (22): 2820-2830 被引量:12
标识
DOI:10.2174/1389557522666220513150907
摘要

Plant derived natural products have multifaceted beneficial roles in human pathophysiology. Plant secondary metabolites have been used as an adjunct medicine for a long time and β- Glucogallin is one such pharmaceutically important plant derived natural product. Β-glucogallin (1-O-galloyl-β-d-glucopyranose), a plant-derived polyphenolic ester, is regarded as the primary metabolite in the biosynthesis of hydrolyzable tannins. It is majorly found in amla, pomegranate, strawberry etc. Owing to its free radical scavenging properties, β-glucogallin (BG) is believed to protect against several diseases like diabetes and related complications like retinopathy, glaucoma, inflammation, hepatic damage, skin damage from UV, etc. Several semisynthetic derivatives of β-Glucogallin are being developed, which have better pharmacokinetic and pharmacodynamic parameters than β-glucogallin. Studies have shown the prophylactic role of β-Glucogallin in developing defence mechanisms against the advent and progression of certain diseases. β- glucogallin formulations have shown a positive effect as a neutraceutical. In this manuscript, we have discussed β-glucogallin, its natural sources, biosynthetic pathways, its semi-synthetic derivatives, and the plethora of its pharmacological activities like antioxidant-antiinflammatory, antidiabetic, cataract-preventing, anti glaucoma, and UV protectant. We have also highlighted various biological pathways, which are modulated by β-glucogallin. The manuscript will convey the importance of β-glucogallin as a compound of natural origin, having multifaceted health benefits.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
可爱的以莲完成签到,获得积分10
刚刚
小夹子完成签到 ,获得积分10
刚刚
不想洗碗完成签到,获得积分10
1秒前
科研通AI5应助沉静寄云采纳,获得10
1秒前
2秒前
科研通AI5应助会飞的野马采纳,获得10
2秒前
海底菠萝发布了新的文献求助10
2秒前
SYLH应助111123123123采纳,获得10
3秒前
3秒前
3秒前
汉堡包应助起床做核酸采纳,获得10
3秒前
xulenglengk完成签到,获得积分10
3秒前
传奇3应助机智的冰蓝采纳,获得10
3秒前
迟大猫应助Jane采纳,获得10
7秒前
优雅的雨发布了新的文献求助10
7秒前
8秒前
8秒前
金新皓发布了新的文献求助10
8秒前
张东泽发布了新的文献求助10
8秒前
8秒前
消消消消气完成签到 ,获得积分10
8秒前
传奇3应助xxx采纳,获得10
9秒前
9秒前
9秒前
舒服的微笑完成签到,获得积分10
11秒前
Neo完成签到,获得积分10
11秒前
12秒前
YOLO发布了新的文献求助10
12秒前
demo1完成签到,获得积分10
13秒前
李子韵完成签到,获得积分10
13秒前
李健的小迷弟应助wendy采纳,获得10
13秒前
13秒前
小巧南琴发布了新的文献求助10
14秒前
14秒前
优雅的雨完成签到,获得积分10
14秒前
15秒前
16秒前
16秒前
大个应助Ywffffff采纳,获得10
17秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Mechanistic Modeling of Gas-Liquid Two-Phase Flow in Pipes 2500
Kelsen’s Legacy: Legal Normativity, International Law and Democracy 1000
Handbook on Inequality and Social Capital 800
Conference Record, IAS Annual Meeting 1977 610
Interest Rate Modeling. Volume 3: Products and Risk Management 600
Interest Rate Modeling. Volume 2: Term Structure Models 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3546676
求助须知:如何正确求助?哪些是违规求助? 3123726
关于积分的说明 9356475
捐赠科研通 2822353
什么是DOI,文献DOI怎么找? 1551369
邀请新用户注册赠送积分活动 723332
科研通“疑难数据库(出版商)”最低求助积分说明 713721