类固醇
抗真菌
芳香化酶
广谱
抗菌剂
计算生物学
化学
生物活性
药理学
生物
组合化学
生物化学
微生物学
激素
癌症
体外
乳腺癌
遗传学
出处
期刊:Mini-reviews in Medicinal Chemistry
[Bentham Science]
日期:2018-04-30
卷期号:18 (9): 745-775
被引量:22
标识
DOI:10.2174/1389557517666171003103245
摘要
Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5α-reductase inhibitors and neuromuscular blocking agents etc. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper is to review the recent advances of steroid-based derivatives mainly focused on their structures and biological applications, which can be employed for further development to discover potential drug candidates.
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