The ratios of central venous to arterial carbon dioxide content and tension to arteriovenous oxygen content are not associated with overall anaerobic metabolism in postoperative cardiac surgery patients

二氧化碳 医学 无氧运动 氧气 二氧化碳 心脏病学 静脉血 心脏指数 心输出量 动脉血 心脏外科 动静脉氧分压差 内科学 麻醉 血压 血流动力学 化学 冲程容积 心率 生理学 有机化学
作者
Osama Abou‐Arab,Rayan Braïk,Pierre Huette,Bélaïd Bouhemad,Emmanuel Lorne,Pierre-Grégoire Guinot
出处
期刊:PLOS ONE [Public Library of Science]
卷期号:13 (10): e0205950-e0205950 被引量:34
标识
DOI:10.1371/journal.pone.0205950
摘要

Background The aim of the present study was to evaluate the ability of the ratios of central venous to arterial carbon dioxide content and tension to arteriovenous oxygen content to predict an increase in oxygen consumption (VO2) upon fluid challenge (FC). Methods and results 110 patients admitted to cardiothoracic ICU and in whom the physician had decided to perform an FC (with 500 ml of Ringer's lactate solution) were included. The arterial pressure, cardiac index (Ci), and arterial and venous blood gas levels were measured before and after FC. VO2 and CO2-O2 derived variables were calculated. VO2 responders were defined as patients showing more than a 15% increase in VO2. Of the 92 FC responders, 43 (46%) were VO2 responders. At baseline, pCO2 gap, C(a-v)O2 were lower in VO2 responders than in VO2 non-responders, and central venous oxygen saturation (ScvO2) was higher in VO2 responders. FC was associated with an increase in MAP, SV, and CI in both groups. With regard to ScvO2, FC was associated with an increase in VO2 non-responders and a decrease in VO2 responders. FC was associated with a decrease in pvCO2 and pCO2 gap in VO2 non-responders only. The pCO2 gap/C(a-v)O2 ratio and C(a-v)CO2 content /C(a-v)O2 content ratio did not change with FC. The CO2 gap content/C(a-v)O2 content ratio and the C(a-v)CO2 content /C(a-v)O2 content ratio did not predict fluid-induced VO2 changes (area under the curve (AUC) [95% confidence interval (CI)] = 0.52 [0.39‒0.64] and 0.53 [0.4–0.65], respectively; p = 0.757 and 0.71, respectively). ScvO2 predicted an increase of more than 15% in the VO2 (AUC [95%CI] = 0.67 [0.55‒0.78]; p<0.0001). Conclusions Our results showed that the ratios of central venous to arterial carbon dioxide content and tension to arteriovenous oxygen content were not predictive of VO2 changes following fluid challenge in postoperative cardiac surgery patients.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
打打应助闫雪采纳,获得10
1秒前
1秒前
露亮发布了新的文献求助10
1秒前
peterlee发布了新的文献求助10
1秒前
congenialboy发布了新的文献求助10
2秒前
苏卿应助zys采纳,获得30
2秒前
科研助手6应助zys采纳,获得10
2秒前
清歌浊酒完成签到,获得积分20
3秒前
jay发布了新的文献求助10
4秒前
热情鹤发布了新的文献求助30
6秒前
香蕉觅云应助帅男采纳,获得30
6秒前
7秒前
10秒前
小二郎应助wenlin采纳,获得10
11秒前
星辰大海应助大喵采纳,获得10
13秒前
14秒前
15秒前
天天快乐应助xxxllllll采纳,获得30
15秒前
小马甲应助amai采纳,获得10
16秒前
16秒前
热情鹤完成签到,获得积分10
17秒前
方便面了吗完成签到,获得积分20
18秒前
18秒前
18秒前
李健的小迷弟应助llllhh采纳,获得10
19秒前
今夜有雨完成签到 ,获得积分10
20秒前
20秒前
20秒前
20秒前
wenlin发布了新的文献求助10
22秒前
王武聪关注了科研通微信公众号
23秒前
peterlee发布了新的文献求助10
24秒前
wish发布了新的文献求助10
24秒前
风清扬应助慈祥的水池采纳,获得50
26秒前
大喵发布了新的文献求助10
26秒前
29秒前
30秒前
31秒前
32秒前
自觉绿草发布了新的文献求助10
33秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989797
求助须知:如何正确求助?哪些是违规求助? 3531914
关于积分的说明 11255516
捐赠科研通 3270597
什么是DOI,文献DOI怎么找? 1805008
邀请新用户注册赠送积分活动 882181
科研通“疑难数据库(出版商)”最低求助积分说明 809190