吞吐量
自动化
计算机科学
连续流动
药物发现
工艺工程
纳米技术
组合化学
系统工程
化学
生化工程
材料科学
工程类
电信
机械工程
生物化学
无线
作者
Junrong Yu,Jiaying Liu,Chaoyi Li,Junrong Huang,Yuxiang Zhu,Hengzhi You
摘要
High-throughput continuous flow technology has emerged as a revolutionary approach in chemical synthesis, offering accelerated experimentation and improved efficiency. With the aid of process analytical technology and automation, this system not only enables rapid optimisation of reaction conditions at the millimole to the picomole scale, but also facilitates automated scale-up synthesis. It can even achieve the self-planning and self-synthesis of small drug molecules with artificial intelligence incorporated in the system. The versatility of the system is highlighted by its compatibility with both electrochemistry and photochemistry, and its significant applications in organic synthesis and drug discovery. This highlight summarises its recent developments and applications, emphasising its significant impact on advancing research across multiple disciplines.
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