光遗传学
生物生产
合成生物学
生物
神经科学
计算机科学
纳米技术
计算生物学
生物技术
材料科学
作者
Moritz Benisch,Stephanie K. Aoki,Mustafa Khammash
标识
DOI:10.1016/j.mib.2023.102404
摘要
Optogenetics is a powerful approach that enables researchers to use light to dynamically manipulate cellular behavior. Since the first published use of optogenetics in synthetic biology, the field has expanded rapidly, yielding a vast array of tools and applications. Despite its immense potential for achieving high spatiotemporal precision, optogenetics has predominantly been employed as a substitute for conventional chemical inducers. In this short review, we discuss key features of microbial optogenetics and highlight applications for understanding biology, cocultures, bioproduction, biomaterials, and therapeutics, in which optogenetics is more fully utilized to realize goals not previously possible by other methods.
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