An integrated chemical characterization based on FT-NIR, and GC–MS for the comparative metabolite profiling of 3 species of the genus Amomum

化学 掺假者 代谢物分析 传统医学 主成分分析 偏最小二乘回归 代谢组学 色谱法 化学计量学 人工智能 数学 计算机科学 医学 统计
作者
Gang He,Shaobing Yang,Yuanzhong Wang
出处
期刊:Analytica Chimica Acta [Elsevier BV]
卷期号:1280: 341869-341869 被引量:21
标识
DOI:10.1016/j.aca.2023.341869
摘要

The fruits and seeds of genus Amomum are well-known as medicinal plants and edible spices, and are used in countries such as China, India and Vietnam to treat malaria, gastrointestinal disorders and indigestion. The morphological differences between different species are relatively small, and technical characterization and identification techniques are needed.Fourier transform near infrared spectroscopy (FT-NIR) and gas chromatography-mass spectrometry (GC-MS), combined with principal component analysis and two-dimensional correlation analysis were used to characterize the chemical differences of Amomum tsao-ko, Amomum koenigii, and Amomum paratsaoko. The targets and pathways for the treatment of diabetes mellitus in three species were predicted using network pharmacology and screened for the corresponding pharmacodynamic components as potential quality markers. The results of "component-target-pathway" network showed that (+)-Nerolidol, 2-Nonanol, α-Terpineol, α-Pinene, 2-Nonanone had high degree values and may be the main active components. Partial least squares-discriminant analysis (PLS-DA) was further used to select for differential metabolites and was identified as a potential quality marker, 11 in total. PLS-DA and residual network (ResNet) classification models were developed for the identification of 3 species of the genus Amomum, ResNet model is more suitable for the identification study of large volume samples.This study characterizes the differences between the three species in a visual way and also provides a reliable technique for their identification, while demonstrating the ability of FT-NIR spectroscopy for fast, easy and accurate species identification. The results of this study lay the foundation for quality evaluation studies of genus Amomum and provide new ideas for the development of new drugs for the treatment of diabetes mellitus.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
榴莲发布了新的文献求助10
1秒前
2秒前
5秒前
桐桐应助Dora采纳,获得10
5秒前
香蕉觅云应助糟糕的铁锤采纳,获得10
5秒前
7秒前
10秒前
10秒前
13秒前
沉静白卉完成签到,获得积分10
14秒前
guo发布了新的文献求助200
14秒前
隐形曼青应助渡川采纳,获得10
14秒前
大海完成签到,获得积分10
14秒前
16秒前
yuyuyu完成签到,获得积分10
17秒前
赘婿应助morena采纳,获得30
17秒前
masheng发布了新的文献求助10
17秒前
落后凝莲完成签到,获得积分20
18秒前
19秒前
隐形曼青应助动听的世立采纳,获得10
20秒前
20秒前
20秒前
西瓜妈妈完成签到,获得积分20
22秒前
时雨完成签到,获得积分10
22秒前
24秒前
24秒前
Ava应助hanchangcun采纳,获得10
25秒前
ElbingX发布了新的文献求助20
25秒前
lemongulf完成签到 ,获得积分10
26秒前
26秒前
机灵的成协完成签到,获得积分10
27秒前
Coral.发布了新的文献求助10
27秒前
ShengjieZi发布了新的文献求助10
28秒前
28秒前
29秒前
29秒前
科研通AI5应助Ultraman45采纳,获得10
30秒前
可爱的函函应助fjiang2003采纳,获得10
31秒前
gky完成签到,获得积分10
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976235
求助须知:如何正确求助?哪些是违规求助? 3520399
关于积分的说明 11203166
捐赠科研通 3256989
什么是DOI,文献DOI怎么找? 1798580
邀请新用户注册赠送积分活动 877738
科研通“疑难数据库(出版商)”最低求助积分说明 806516