自愈水凝胶
壳聚糖
药物输送
纤维素乙醇
背景(考古学)
瓜尔胶
化学
透明质酸
纳米技术
纤维素
材料科学
生物化学
有机化学
医学
生物
古生物学
解剖
作者
Udaykumar G. Vegad,Megha Patel,Dignesh Khunt,Ožbej Zupančič,Sanjay Chauhan,Amrit Paudel
标识
DOI:10.3389/fbioe.2023.1270364
摘要
Over the past several decades, there has been significant growth in the design and development of more efficient and advanced biomaterials based on non-cellulosic biological macromolecules. In this context, hydrogels based on stimuli-responsive non-cellulosic biological macromolecules have garnered significant attention because of their intrinsic physicochemical properties, biological characteristics, and sustainability. Due to their capacity to adapt to physiological pHs with rapid and reversible changes, several researchers have investigated pH-responsive-based non-cellulosic polymers from various materials. pH-responsive hydrogels release therapeutic substances in response to pH changes, providing tailored administration, fewer side effects, and improved treatment efficacy while reducing tissue damage. Because of these qualities, they have been shown to be useful in a wide variety of applications, including the administration of chemotherapeutic drugs, biological material, and natural components. The pH-sensitive biopolymers that are utilized most frequently include chitosan, alginate, hyaluronic acid, guar gum, and dextran. In this review article, the emphasis is placed on pH stimuli-responsive materials that are based on biological macromolecules for the purposes of drug administration.
科研通智能强力驱动
Strongly Powered by AbleSci AI