材料科学
纳米技术
镜头(地质)
光学显微镜
显微镜
光学
光流学
纳米颗粒
油浸
折射率
显微镜
微流控
光电子学
扫描电子显微镜
物理
复合材料
作者
Weicheng Wang,Bing Yan,Haiyan Wang,Yue Chen,Xiuyu Nie,Changfeng Yi,Zengbo Wang,Zushun Xu,Jing Zeng,Wen Fan
出处
期刊:Small
[Wiley]
日期:2023-03-10
卷期号:19 (23)
被引量:1
标识
DOI:10.1002/smll.202207596
摘要
Super-resolution optical imaging techniques can break the optical diffraction limit, thus providing unique opportunities to visualize the microscopic world at the nanoscale. Although near-field optical microscopy techniques have been proven to achieve significantly improved imaging resolution, most near-field approaches still suffer from a narrow field of view (FOV) or difficulty in obtaining wide-field images in real time, which may limit their widespread and diverse applications. Here, the authors experimentally demonstrate an optical microscope magnification and image enhancement approach by using a submillimeter-sized solid immersion lens (SIL) assembled by densely-packed 15 nm TiO2 nanoparticles through a silicone oil two-step dehydration method. This TiO2 nanoparticle-assembled SIL can achieve both high transparency and high refractive index, as well as sufficient mechanical strength and easy-to-handle size, thus providing a fast, wide-field, real-time, non-destructive, and low-cost solution for improving the quality of optical microscopic observation of a variety of samples, including nanomaterials, cancer cells, and living cells or bacteria under conventional optical microscopes. This study provides an attractive alternative to simplify the fabrication and applications of high-performance SILs.
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