医学
骨盆
鼻咽癌
胸部(昆虫解剖学)
病变
骨闪烁照相术
放射科
核医学
骨转移
转移
病理
癌症
放射治疗
内科学
解剖
作者
Yuting Fang,Shoucong Chen,Yuanfan Xu,Meng‐Yun Qiang,Changjuan Tao,Shuang Huang,Lei Wang,Xiaozhong Chen,Caineng Cao
出处
期刊:Nuclear Medicine Communications
[Ovid Technologies (Wolters Kluwer)]
日期:2023-03-10
卷期号:44 (6): 457-462
标识
DOI:10.1097/mnm.0000000000001682
摘要
The purpose of this study is to evaluate the role of 18 fluorodeoxyglucose ( 18 F) PET/MRI ( 18 F-FDG PET/MRI) for detecting bone metastasis in nasopharyngeal carcinoma (NPC).Between May 2017 and May 2021, 58 histologically proven NPC patients who underwent both 18 F-FDG PET/MRI and 99m Tc-MDP planar bone scintigraphy (PBS) for tumor staging were included. With the exception of the head, the skeletal system was classified into four groups: the spine, the pelvis, the thorax and the appendix.Nine (15.5 %) of 58 patients were confirmed to have bone metastasis. There was no statistical difference between PET/MRI and PBS in patient-based analysis ( P = 0.125). One patient with a super scan was confirmed to have extensive and diffuse bone metastases and excluded for lesion-based analysis. Of the 57 patients, all 48 true metastatic lesions were positive in PET/MRI whereas only 24 true metastatic lesions were positive in PBS (spine: 8, thorax: 0, pelvis: 11 and appendix: 5). PET/MRI was observed to be more sensitive than PBS in lesion-based analysis (sensitivity 100.0% versus 50.0 %; P < 0.001).Compared with PBS for tumor staging of NPC, PET/MRI was observed to be more sensitive in the lesion-based analysis of bone metastasis.
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