Investigating the Impact of Segregation and Integration on Infection Dynamics: Analysis of a Cholera Model in a Two-Population System

霍乱 动力学(音乐) 人口 系统动力学 计算机科学 地理 生物 病毒学 人口学 心理学 社会学 人工智能 教育学
作者
Omar El Deeb,Antoine Matar
出处
期刊:Cold Spring Harbor Laboratory - medRxiv
标识
DOI:10.1101/2024.05.01.24306689
摘要

Abstract We present a novel dynamic model designed to depict Cholera outbreaks within a two-population framework featuring two environmental reservoirs. The model is designed to emulate the impact of segregation or integration between two populations on the transmission of the disease and infections throughout the entire community, both with and without non-medicinal interventions. This is achieved by allowing infectious individuals to interact with the reservoir of the alternate population at different levels of suppression, in addition to their regular interaction with their own reservoir. We find out that increased suppression of cross community interaction reduces the number of infections in the overall population as well as in the population with less contamination and contact. Additionally, we predict significant delays in the occurrence of peak infections, affording public health authorities crucial time for intervention. Lowering cross-immunity interactions also leads to a decrease in bacterial concentrations in environmental reservoirs. Finally, we demonstrate that non-medicinal interventions, including sanitation and water purification, would significantly reduce and delay infections, providing a valuable time frame for implementing additional medicinal measures.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
JamesOliver应助bofu采纳,获得30
刚刚
yanzu发布了新的文献求助10
刚刚
奋斗的杰发布了新的文献求助10
刚刚
吃饱了就晒太阳完成签到,获得积分10
刚刚
狂野怜蕾完成签到,获得积分10
1秒前
肖良啊完成签到,获得积分10
2秒前
2秒前
3秒前
qqs发布了新的文献求助10
4秒前
Raxiny发布了新的文献求助10
4秒前
难过的蘑菇完成签到,获得积分10
6秒前
肖良啊发布了新的文献求助10
6秒前
zhangsan5421完成签到,获得积分10
6秒前
yu完成签到 ,获得积分10
7秒前
cheryl发布了新的文献求助10
9秒前
9秒前
杨涵完成签到,获得积分20
10秒前
小二郎应助swordlee采纳,获得10
10秒前
Raxiny完成签到,获得积分10
10秒前
12秒前
36456657应助michellewu采纳,获得10
12秒前
半斤发布了新的文献求助20
12秒前
12秒前
13秒前
樱桃小贩完成签到,获得积分10
15秒前
田様应助yyy采纳,获得10
15秒前
Irissun完成签到,获得积分10
15秒前
道可道发布了新的文献求助10
16秒前
Jason举报困困卷毛猫求助涉嫌违规
16秒前
傲娇的寻凝完成签到,获得积分10
16秒前
科研小白完成签到,获得积分10
17秒前
17秒前
萧七七完成签到,获得积分10
18秒前
114555完成签到,获得积分10
18秒前
18秒前
19秒前
愉快棒棒糖完成签到,获得积分10
21秒前
fls221完成签到,获得积分10
21秒前
mirrovo完成签到 ,获得积分10
21秒前
21秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Mechanistic Modeling of Gas-Liquid Two-Phase Flow in Pipes 2500
Kelsen’s Legacy: Legal Normativity, International Law and Democracy 1000
Handbook on Inequality and Social Capital 800
Conference Record, IAS Annual Meeting 1977 610
Interest Rate Modeling. Volume 3: Products and Risk Management 600
Interest Rate Modeling. Volume 2: Term Structure Models 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3546508
求助须知:如何正确求助?哪些是违规求助? 3123622
关于积分的说明 9356111
捐赠科研通 2822292
什么是DOI,文献DOI怎么找? 1551314
邀请新用户注册赠送积分活动 723303
科研通“疑难数据库(出版商)”最低求助积分说明 713699