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HDR brachytherapy afterloader quality assurance optimization using monolithic silicon strip detectors

质量保证 近距离放射治疗 克尔玛 停留时间 探测器 计算机科学 核医学 物理 医学物理学 光学 剂量学 工程类 医学 放射治疗 放射科 运营管理 外部质量评估 临床心理学
作者
Broady Hunt,Dean Cutajar,Marco Petasecca,Anatoly Rosenfeld,Andrew Howie,Joseph Bucci,Joel Poder
出处
期刊:Medical Physics [Wiley]
卷期号:51 (7): 4581-4590 被引量:1
标识
DOI:10.1002/mp.17240
摘要

Abstract Background There currently exists no widespread high dose‐rate (HDR) brachytherapy afterloader quality assurance (QA) tool for simultaneously assessing the afterloader's positional, temporal, transit velocity and air kerma strength accuracy. Purpose The purpose of this study was to develop a precise and rigorous technique for performing daily QA of HDR brachytherapy afterloaders, incorporating QA of: dwell position accuracy, dwell time accuracy, transit velocity consistency and relative air kerma strength (AKS) of an Ir‐192 source. Method A Sharp ProGuide 240 mm catheter (Elekta Brachytherapy, Veenendaal, The Netherlands) was fixed 5 mm above a 256 channel epitaxial diode array ‘dose magnifying glass’ (DMG256) (Centre for Medical and Radiation Physics, University of Wollongong). Three dwell positions, each of 5.0 s dwell times, were spaced 13.0 mm apart along the array with the Flexitron HDR afterloader (Elekta Brachytherapy, Veenendaal, The Netherlands). The DMG256 was connected to a data acquisition system (DAQ) and a computer via USB2.0 link for live readout and post‐processing. The outputted data files were analyzed using a Python script to provide positional and temporal localization of the Ir‐192 source by tracking the centroid of the detected response. Measurements were repeated on a weekly basis, for a period of 5 weeks to determine the consistency of the measured parameters over an extended period. Results Using the DMG256 for relative AKS measurements resulted in measured values within 0.6%–3.0% of the expected activity over a 7‐week period. The sub‐millisecond temporal accuracy of the device allowed for measurements of the transit velocity with an average of (10.88 ± 1.01) cm/s for 13 mm steps. The dwell position localization for 1, 2, 3, 5, and 10 mm steps had an accuracy between 0.1 and 0.3 mm (3σ), with a fixed temporal accuracy of 10 ms. Conclusion The DMG256 silicon strip detector allows for clinics to perform rigorous daily QA of HDR afterloader dwell position and dwell time accuracy with greater precision than the current standard methodology using closed circuit television and a stopwatch. Additionally, DMG256 unlocks the ability to perform measurements of transit velocity/time and relative AKS, which are not possible using current standard techniques.
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