HDR brachytherapy afterloader quality assurance optimization using monolithic silicon strip detectors

质量保证 近距离放射治疗 克尔玛 停留时间 探测器 计算机科学 核医学 物理 医学物理学 光学 剂量学 工程类 医学 放射治疗 放射科 运营管理 外部质量评估 临床心理学
作者
Broady Hunt,Dean Cutajar,Marco Petasecca,Anatoly Rosenfeld,Andrew Howie,Joseph Bucci,Joel Poder
出处
期刊:Medical Physics [Wiley]
卷期号:51 (7): 4581-4590 被引量:1
标识
DOI:10.1002/mp.17240
摘要

Abstract Background There currently exists no widespread high dose‐rate (HDR) brachytherapy afterloader quality assurance (QA) tool for simultaneously assessing the afterloader's positional, temporal, transit velocity and air kerma strength accuracy. Purpose The purpose of this study was to develop a precise and rigorous technique for performing daily QA of HDR brachytherapy afterloaders, incorporating QA of: dwell position accuracy, dwell time accuracy, transit velocity consistency and relative air kerma strength (AKS) of an Ir‐192 source. Method A Sharp ProGuide 240 mm catheter (Elekta Brachytherapy, Veenendaal, The Netherlands) was fixed 5 mm above a 256 channel epitaxial diode array ‘dose magnifying glass’ (DMG256) (Centre for Medical and Radiation Physics, University of Wollongong). Three dwell positions, each of 5.0 s dwell times, were spaced 13.0 mm apart along the array with the Flexitron HDR afterloader (Elekta Brachytherapy, Veenendaal, The Netherlands). The DMG256 was connected to a data acquisition system (DAQ) and a computer via USB2.0 link for live readout and post‐processing. The outputted data files were analyzed using a Python script to provide positional and temporal localization of the Ir‐192 source by tracking the centroid of the detected response. Measurements were repeated on a weekly basis, for a period of 5 weeks to determine the consistency of the measured parameters over an extended period. Results Using the DMG256 for relative AKS measurements resulted in measured values within 0.6%–3.0% of the expected activity over a 7‐week period. The sub‐millisecond temporal accuracy of the device allowed for measurements of the transit velocity with an average of (10.88 ± 1.01) cm/s for 13 mm steps. The dwell position localization for 1, 2, 3, 5, and 10 mm steps had an accuracy between 0.1 and 0.3 mm (3σ), with a fixed temporal accuracy of 10 ms. Conclusion The DMG256 silicon strip detector allows for clinics to perform rigorous daily QA of HDR afterloader dwell position and dwell time accuracy with greater precision than the current standard methodology using closed circuit television and a stopwatch. Additionally, DMG256 unlocks the ability to perform measurements of transit velocity/time and relative AKS, which are not possible using current standard techniques.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
健壮凡桃发布了新的文献求助10
1秒前
若杉发布了新的文献求助10
1秒前
CipherSage应助贪玩绮山采纳,获得10
1秒前
2秒前
cs完成签到,获得积分10
2秒前
2秒前
2秒前
Shannon发布了新的文献求助10
3秒前
sun完成签到,获得积分10
3秒前
yzm完成签到,获得积分10
3秒前
3秒前
zhhua完成签到,获得积分10
4秒前
红豆521完成签到,获得积分20
4秒前
4秒前
在水一方应助曾蕙茹采纳,获得10
5秒前
细心的日记本完成签到,获得积分10
6秒前
浅苏完成签到,获得积分10
6秒前
Orange应助小宋采纳,获得10
6秒前
xff完成签到 ,获得积分10
6秒前
曾经不言发布了新的文献求助10
7秒前
7秒前
缓慢的书蕾关注了科研通微信公众号
7秒前
7秒前
7秒前
scz发布了新的文献求助10
7秒前
Islet发布了新的文献求助10
8秒前
8秒前
8秒前
情怀应助糟糕的铁锤采纳,获得10
9秒前
tingalan应助若杉采纳,获得10
9秒前
汉堡包应助红豆521采纳,获得10
9秒前
9秒前
Meron发布了新的文献求助10
9秒前
善学以致用应助吃肉璇璇采纳,获得10
10秒前
杨羕发布了新的文献求助10
10秒前
积极灵寒完成签到 ,获得积分20
11秒前
11秒前
11秒前
君打豆发布了新的文献求助10
11秒前
11秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
Encyclopedia of Quaternary Science Reference Third edition 6000
Encyclopedia of Forensic and Legal Medicine Third Edition 5000
Introduction to strong mixing conditions volume 1-3 5000
Aerospace Engineering Education During the First Century of Flight 3000
Agyptische Geschichte der 21.30. Dynastie 3000
Les Mantodea de guyane 2000
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 计算机科学 有机化学 物理 生物化学 纳米技术 复合材料 内科学 化学工程 人工智能 催化作用 遗传学 数学 基因 量子力学 物理化学
热门帖子
关注 科研通微信公众号,转发送积分 5784462
求助须知:如何正确求助?哪些是违规求助? 5682526
关于积分的说明 15464250
捐赠科研通 4913580
什么是DOI,文献DOI怎么找? 2644772
邀请新用户注册赠送积分活动 1592662
关于科研通互助平台的介绍 1547148