Performances of different classification criteria for systemic lupus erythematosus in a single-center cohort from Turkey

医学 队列 内科学 抗磷脂综合征 金标准(测试) 预测值 系统性红斑狼疮 正谓词值 病历 胃肠病学 疾病 血栓形成
作者
Ege Sinan Torun,Erdem Bektaş,Fatih Kemik,Murat Bektaş,C. Cetin,Y. Yalçınkaya,Bahar Artım-Esen,Ahmet Gül,Murat İnanç
出处
期刊:Lupus [SAGE]
卷期号:31 (12): 1536-1543
标识
DOI:10.1177/09612033221126866
摘要

Objective Sensitivity and specificity of SLE classification criteria may vary in different populations and clinical settings. In this study, we aimed to compare the performances of three criteria sets/rules (1997, 2012, and 2019) in a large cohort of patients and relevant diseased controls. Methods The medical records of consecutive SLE patients and diseased controls were reviewed for clinical and laboratory features relevant to all sets of criteria. Criteria sets/rules were analyzed based on sensitivity, positive predictive value, specificity, and negative predictive value, using clinical diagnosis with at least 6 months of follow-up as the gold standard. A subgroup analysis was performed in ANA positive patients. Results A total of 393 SLE patients and 308 non-SLE diseased controls were included. Sensitivity was 78.4% for 1997 criteria and was more than 90% for both 2012 (91.9%) and 2019 (94.4%) criteria. Specificity was the highest (95.1%) for 1997 ACR criteria, 91.5% for 2012 SLICC criteria and 91.2% for 2019 EULAR/ACR criteria. When only ANA positive patients were analyzed, sensitivity of each criteria increased by 1%, 0.8%, and 2.2%, respectively. Specificity of 1997 criteria decreased by 2% and specificity of 2012 and 2019 criteria both decreased to less than 90%. Conclusion EULAR/ACR criteria were more sensitive than 1997 criteria and had a comparable performance with SLICC criteria. When only ANA positive patients were analyzed, the presence of false positive results (originated from patients with Sjögren’s disease and antiphospholipid syndrome mainly) decreased the specificity of both SLICC and EULAR/ACR criteria.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
kerrie应助dty采纳,获得10
2秒前
3秒前
天天快乐应助Ss采纳,获得10
7秒前
长风发布了新的文献求助10
7秒前
Zilch完成签到 ,获得积分10
8秒前
wen完成签到,获得积分10
9秒前
科研通AI2S应助sun1采纳,获得30
9秒前
jixuchance发布了新的文献求助10
9秒前
xiaoou完成签到 ,获得积分10
10秒前
包容冰薇完成签到,获得积分10
10秒前
英姑应助稳重宛白采纳,获得10
11秒前
Lion完成签到,获得积分20
12秒前
12秒前
13秒前
科研通AI2S应助健壮的丹萱采纳,获得10
15秒前
胡乱说兔的熊完成签到,获得积分10
15秒前
16秒前
16秒前
17秒前
深情安青应助jixuchance采纳,获得10
17秒前
戴眼镜的山人关注了科研通微信公众号
18秒前
19秒前
19秒前
LV发布了新的文献求助10
21秒前
聪明小丸子完成签到 ,获得积分10
21秒前
21秒前
CipherSage应助称心寒松采纳,获得10
21秒前
Owen应助食堂里的明湖鸭采纳,获得10
22秒前
华仔应助等风来采纳,获得10
23秒前
24秒前
天天快乐应助小L采纳,获得10
24秒前
西子阳发布了新的文献求助10
25秒前
多情寒珊发布了新的文献求助10
26秒前
大个应助科研通管家采纳,获得10
29秒前
Akim应助科研通管家采纳,获得10
29秒前
29秒前
打打应助科研通管家采纳,获得10
29秒前
邓力应助科研通管家采纳,获得20
29秒前
在水一方应助科研通管家采纳,获得10
30秒前
高分求助中
Sustainability in Tides Chemistry 1500
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
CLSI EP47 Evaluation of Reagent Carryover Effects on Test Results, 1st Edition 800
Threaded Harmony: A Sustainable Approach to Fashion 799
Livre et militantisme : La Cité éditeur 1958-1967 500
Retention of title in secured transactions law from a creditor's perspective: A comparative analysis of selected (non-)functional approaches 500
"Sixth plenary session of the Eighth Central Committee of the Communist Party of China" 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3055724
求助须知:如何正确求助?哪些是违规求助? 2712356
关于积分的说明 7431187
捐赠科研通 2357329
什么是DOI,文献DOI怎么找? 1248746
科研通“疑难数据库(出版商)”最低求助积分说明 606786
版权声明 596144