亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Performances of different classification criteria for systemic lupus erythematosus in a single-center cohort from Turkey

医学 队列 内科学 抗磷脂综合征 金标准(测试) 预测值 系统性红斑狼疮 正谓词值 病历 胃肠病学 疾病 血栓形成
作者
Ege Sinan Torun,Erdem Bektaş,Fatih Kemik,Murat Bektaş,C. Cetin,Y. Yalçınkaya,Bahar Artım-Esen,Ahmet Gül,Murat İnanç
出处
期刊:Lupus [SAGE]
卷期号:31 (12): 1536-1543
标识
DOI:10.1177/09612033221126866
摘要

Objective Sensitivity and specificity of SLE classification criteria may vary in different populations and clinical settings. In this study, we aimed to compare the performances of three criteria sets/rules (1997, 2012, and 2019) in a large cohort of patients and relevant diseased controls. Methods The medical records of consecutive SLE patients and diseased controls were reviewed for clinical and laboratory features relevant to all sets of criteria. Criteria sets/rules were analyzed based on sensitivity, positive predictive value, specificity, and negative predictive value, using clinical diagnosis with at least 6 months of follow-up as the gold standard. A subgroup analysis was performed in ANA positive patients. Results A total of 393 SLE patients and 308 non-SLE diseased controls were included. Sensitivity was 78.4% for 1997 criteria and was more than 90% for both 2012 (91.9%) and 2019 (94.4%) criteria. Specificity was the highest (95.1%) for 1997 ACR criteria, 91.5% for 2012 SLICC criteria and 91.2% for 2019 EULAR/ACR criteria. When only ANA positive patients were analyzed, sensitivity of each criteria increased by 1%, 0.8%, and 2.2%, respectively. Specificity of 1997 criteria decreased by 2% and specificity of 2012 and 2019 criteria both decreased to less than 90%. Conclusion EULAR/ACR criteria were more sensitive than 1997 criteria and had a comparable performance with SLICC criteria. When only ANA positive patients were analyzed, the presence of false positive results (originated from patients with Sjögren’s disease and antiphospholipid syndrome mainly) decreased the specificity of both SLICC and EULAR/ACR criteria.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
汉堡包应助liubo采纳,获得10
2秒前
科目三应助Original采纳,获得10
12秒前
20秒前
风中小刺猬完成签到,获得积分10
21秒前
Owen应助cindy采纳,获得10
21秒前
Original发布了新的文献求助10
25秒前
largpark完成签到 ,获得积分10
27秒前
29秒前
30秒前
cindy发布了新的文献求助10
33秒前
liubo发布了新的文献求助10
35秒前
Original完成签到,获得积分10
37秒前
cindy完成签到,获得积分10
59秒前
爆米花应助科研通管家采纳,获得10
1分钟前
CATH完成签到 ,获得积分10
1分钟前
雨天爱吃冰淇淋完成签到 ,获得积分10
1分钟前
2分钟前
金钰贝儿完成签到,获得积分10
3分钟前
qujinzhi完成签到 ,获得积分10
3分钟前
Ava应助李小猫采纳,获得10
3分钟前
李小猫完成签到,获得积分10
3分钟前
3分钟前
李小猫发布了新的文献求助10
3分钟前
奋斗的杰发布了新的文献求助10
5分钟前
ang完成签到,获得积分10
5分钟前
6分钟前
隐形曼青应助奋斗的杰采纳,获得10
6分钟前
7分钟前
7分钟前
wrl2023发布了新的文献求助10
7分钟前
8分钟前
奋斗的杰发布了新的文献求助10
8分钟前
辣椒完成签到 ,获得积分10
9分钟前
9分钟前
9分钟前
123关闭了123文献求助
9分钟前
丘比特应助救救小王叭采纳,获得10
10分钟前
10分钟前
11分钟前
科研通AI2S应助科研通管家采纳,获得10
11分钟前
高分求助中
Evolution 10000
ISSN 2159-8274 EISSN 2159-8290 1000
Becoming: An Introduction to Jung's Concept of Individuation 600
Ore genesis in the Zambian Copperbelt with particular reference to the northern sector of the Chambishi basin 500
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
A new species of Velataspis (Hemiptera Coccoidea Diaspididae) from tea in Assam 500
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3162323
求助须知:如何正确求助?哪些是违规求助? 2813330
关于积分的说明 7899698
捐赠科研通 2472818
什么是DOI,文献DOI怎么找? 1316528
科研通“疑难数据库(出版商)”最低求助积分说明 631365
版权声明 602142