Time variation of ammonia, acetone, isoprene and ethanol in breath: a quantitative SIFT-MS study over 30 days

异戊二烯 乙醛 丙酮 化学 气体分析呼吸 乙醇 代谢物 呼气 色谱法 环境化学 有机化学 生物化学 医学 麻醉 聚合物 共聚物
作者
Ann M. Diskin,Patrik Španěl,David Smith
出处
期刊:Physiological Measurement [IOP Publishing]
卷期号:24 (1): 107-119 被引量:216
标识
DOI:10.1088/0967-3334/24/1/308
摘要

A study of the concentrations of the common breath metabolites ammonia, acetone, isoprene, ethanol and acetaldehyde in the breath of five subjects over a period of 30 days has been carried out. Breath samples were taken and analysed in the early morning on arrival at the laboratory. The real time analyses of three consecutive breath exhalations were carried out using selected ion flow tube mass spectrometry (SIFT-MS) on line to the instrument. Sufficient data were obtained to allow meaningful concentration distributions to be obtained for ammonia, acetone, isoprene and ethanol. These showed that the ammonia, acetone and isoprene concentrations exhibited sensibly normal distributions, with coefficients of variation of typically 0.3. Obvious and statistically significant (p < 0.01) differences are apparent in the mean concentrations of these metabolites between the five individuals. The acetaldehyde concentrations were relatively low and close to the instrument detection limit, and the differences between the mean concentrations of the five subjects were not statistically significant (p = 0.4), so distributions were not obtained. The mean concentrations, in parts per billion (ppb), of each metabolite range amongst the five subjects are as follows: ammonia, 422-2389: acetone, 293-870; isoprene, 55-121; ethanol, 27-153; acetaldehyde, 2-5. There are no obvious patterns in the distributions of these particular metabolites for these individuals, except that the ammonia levels were greatest in the breath of the two oldest subjects.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
大牛顿发布了新的文献求助10
1秒前
善学以致用应助siyin采纳,获得10
2秒前
弥生妖刀完成签到,获得积分10
2秒前
2秒前
3秒前
tyy发布了新的文献求助10
3秒前
酷炫翠桃应助多情万宝路采纳,获得10
3秒前
小金鱼儿发布了新的文献求助10
3秒前
天天快乐应助Albertxkcj采纳,获得10
3秒前
negolos完成签到,获得积分10
3秒前
Tac1完成签到,获得积分10
3秒前
4秒前
4秒前
schnappi完成签到,获得积分10
4秒前
Stefani发布了新的文献求助30
5秒前
三七发布了新的文献求助10
6秒前
小白发布了新的文献求助10
7秒前
zzj512682701完成签到,获得积分10
7秒前
pepsisery完成签到,获得积分10
7秒前
7秒前
晓军发布了新的文献求助10
8秒前
8秒前
小六发布了新的文献求助10
9秒前
赘婿应助靓丽的海亦采纳,获得10
9秒前
10秒前
roser发布了新的文献求助10
11秒前
z1z1z发布了新的文献求助20
12秒前
12秒前
HAL9000完成签到,获得积分10
12秒前
13秒前
zzj512682701发布了新的文献求助10
13秒前
13秒前
典雅碧空应助小涛采纳,获得10
13秒前
苏夏完成签到 ,获得积分10
13秒前
biomichael发布了新的文献求助10
13秒前
情怀应助ottsannn采纳,获得10
14秒前
顾矜应助楼松思采纳,获得10
14秒前
量子星尘发布了新的文献求助10
15秒前
拼搏金鱼完成签到,获得积分20
16秒前
16秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969458
求助须知:如何正确求助?哪些是违规求助? 3514286
关于积分的说明 11173363
捐赠科研通 3249652
什么是DOI,文献DOI怎么找? 1794948
邀请新用户注册赠送积分活动 875501
科研通“疑难数据库(出版商)”最低求助积分说明 804836