复苏
医学
灌注
败血症
组织缺氧
休克(循环)
缺氧(环境)
重症监护医学
内科学
血乳酸
心脏病学
无氧运动
麻醉
生理学
血压
氧气
心率
有机化学
化学
作者
Jan Bakker,Radu Postelnicu,Vikramjit Mukherjee
标识
DOI:10.1016/j.ccc.2019.08.009
摘要
There is a tight relationship between lactate levels (and its changes over time) with morbidity and mortality and the presence of tissue hypoxia/hypoperfusion in both models of shock and clinical studies. These findings have placed lactate in the center of guiding resuscitation in patients with increased lactate levels. However, given the complex metabolism and clearance of lactate, especially in sepsis, the actual use of lactate is more complex than suggested by some guidelines. By using other markers of tissue hypoperfusion together with lactate levels provides a more solid framework to guide the initial hours of resuscitation.
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