水平基因转移
生物
生物膜
机制(生物学)
转导(生物物理学)
基因
遗传学
流动遗传元素
微生物学
细菌
基因组
生物物理学
认识论
哲学
作者
Kimihiro Abe,Nobuhiko Nomura,Satoru Suzuki
标识
DOI:10.1093/femsec/fiaa031
摘要
ABSTRACT Biofilms in water environments are thought to be hot spots for horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). ARGs can be spread via HGT, though mechanisms are known and have been shown to depend on the environment, bacterial communities and mobile genetic elements. Classically, HGT mechanisms include conjugation, transformation and transduction; more recently, membrane vesicles (MVs) have been reported as DNA reservoirs implicated in interspecies HGT. Here, we review the current knowledge on the HGT mechanisms with a focus on the role of MVs and the methodological innovations in the HGT research.
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