Normal Systolic and Diastolic Functions of the Left Ventricle and Left Atrium by Cine Magnetic Resonance Imaging

心室 医学 心脏病学 磁共振成像 血管病学 内科学 冲程容积 舒张期 体表面积 左心房 收缩末期容积 射血分数 核医学 放射科 血压 心力衰竭 心房颤动
作者
Wen‐Yih Isaac Tseng,Ta-Yu Liao,Jaw‐Lin Wang
出处
期刊:Journal of Cardiovascular Magnetic Resonance [Springer Nature]
卷期号:4 (4): 443-457 被引量:60
标识
DOI:10.1081/jcmr-120016383
摘要

Volume and phase characteristics of the left ventricle (LV) and left atrium (LA) were assessed in 31 healthy Asian adults (19 males and 12 females) using cine magnetic resonance imaging (MRI) and an automated boundary detection algorithm. Volume indexes of the LV and LA were smaller than published results obtained mostly from Westerners. Other than LV mass index and percent emptying of the LA, there was no gender difference in all LV/LA indexes. In associating LV/LA functions with the body size and heart rate (HR), we found that LV mass and the minimum LA volume correlated strongly with the body surface area, the maximum LA volume and the reservoir volume correlated strongly with the body weight, and the time to LV peak-filling rate (LVPFRt) and the time to LA peak-emptying rate (LAPERt) correlated strongly with the HR. In associating LV with LA functions, we found that LA conduit volume contributed more than 50% of the LV stroke volume, and correlated with both systolic and diastolic functions of the LV. Moreover, LVPFRt and LAPERt were virtually identical, indicating a mechanical coupling between LV and LA during diastole. In conclusion, using time-resolved, three-dimensional volume data obtained from cine MRI, we have established normative values of LV and LA functions and their functional relationships in healthy Asian adults. The imaging acquisition protocol, data analysis algorithms, and the established normative values provide the basis for the study of left heart function in patients.
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