2-Aminobiphenyl Palladacycles: The “Most Powerful” Precatalysts in C–C and C–Heteroatom Cross-Couplings

New approaches to the Pd-catalysis employing palladacycle precatalysts have been recently developed. Breakthroughs in this area using 2-aminobiphenyl palladacycle precatalysts are highlighted. High reactivity and selectivity are achieved for the C–C and C–heteroatom bond formation under mild reaction conditions.