Discontinuation of etanercept after achievement of sustained remission in patients with rheumatoid arthritis who initially had moderate disease activity—results from the ENCOURAGE study, a prospective, international, multicenter randomized study

Journal Article Discontinuation of etanercept after achievement of sustained remission in patients with rheumatoid arthritis who initially had moderate disease activity—results from the ENCOURAGE study, a prospective, international, multicenter randomized study Get access Hisashi Yamanaka, Hisashi Yamanaka Institute of Rheumatology, Tokyo Women’s Medical University, Japan, Correspondence to: Hisashi Yamanaka, MD, PhD, Director, Professor of Medicine and Rheumatology, Institute of Rheumatology, Tokyo Women's Medical University, 162-0054 10-22 Kawada-cho, Shinjuku-ku, Tokyo, Japan. Tel: +81 352691711, +81 352691725. Fax: +81 352691726. E-mail: yamanaka@twmu.ac.jp, hisashi@pc4.so-net.ne.jp Search for other works by this author on: Oxford Academic Google Scholar Shouhei Nagaoka, Shouhei Nagaoka Internal Department of Rheumatology, Yokohama Minami Kyosai Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Soo-Kon Lee, Soo-Kon Lee Department of Rheumatology, Yonsei University College of Medicine, Korea, Search for other works by this author on: Oxford Academic Google Scholar Sang-Cheol Bae, Sang-Cheol Bae Hanyang University Hospital for Rheumatic Diseases, Korea, Search for other works by this author on: Oxford Academic Google Scholar Tsuyoshi Kasama, Tsuyoshi Kasama Department of Rheumatology, Showa University Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Hitomi Kobayashi, Hitomi Kobayashi Department of Internal Medicine, Itabashi Chuo Medical Center, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yuichi Nishioka, Yuichi Nishioka Department of Rheumatism, Nishioka Clinic for Rheumatic Diseases and Allergic Diseases, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yukitaka Ueki, Yukitaka Ueki Rheumatic Diseases Center, Sasebo Chuo Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yohei Seto, Yohei Seto Institute of Rheumatology, Tokyo Women’s Medical University, Japan, Search for other works by this author on: Oxford Academic Google Scholar Makoto Nishinarita, Makoto Nishinarita Department of Internal Medicine and Rheumatology, Nishinarita Clinic, Japan, Search for other works by this author on: Oxford Academic Google Scholar ... Show more Naoto Tamura, Naoto Tamura Department of Internal Medicine and Rheumatology, Juntendo University Faculty of Medicine, Japan, Search for other works by this author on: Oxford Academic Google Scholar Noriko Kimura, Noriko Kimura Division of Rheumatology, Department of Internal Medicine Keio University School of Medicine, Japan, Search for other works by this author on: Oxford Academic Google Scholar Kazuyoshi Saito, Kazuyoshi Saito The 1st Department of Internal Medicine, School of Medicine University of Occupational & Environmental Health, Japan, Search for other works by this author on: Oxford Academic Google Scholar Tetsuya Tomita, Tetsuya Tomita Department of Orthopedic Surgery, Osaka University Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yasushi Nawata, Yasushi Nawata Center for Rheumatic Diseases, Chibaken Saiseikai Narashino Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Sadahiro Suzuki, Sadahiro Suzuki Department of Connecting Tissue Disease, Shinonoi General Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yoshiaki Ishigatsubo, Yoshiaki Ishigatsubo Rheumatology, Hematology, Infectious Diseases, Yokohama City University Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yasuhiko Munakata, Yasuhiko Munakata Internal Medicine, Rheumatology, Taihakusakura Hospital, Japan, Search for other works by this author on: Oxford Academic Google Scholar Yuichi Makino, Yuichi Makino The 2nd Department of Internal Medicine, Asahikawa Medical University Hospital, Japan, and Search for other works by this author on: Oxford Academic Google Scholar Eisuke Inoue, Eisuke Inoue Division of Biostatistics, National Center for Child Health and Development, Japan Search for other works by this author on: Oxford Academic Google Scholar Yoshiya Tanaka, Yoshiya Tanaka The 1st Department of Internal Medicine, School of Medicine University of Occupational & Environmental Health, Japan, Search for other works by this author on: Oxford Academic Google Scholar Tsutomu Takeuchi, Tsutomu Takeuchi Division of Rheumatology, Department of Internal Medicine Keio University School of Medicine, Japan, Search for other works by this author on: Oxford Academic Google Scholar the ENCOURAGE study group the ENCOURAGE study group Search for other works by this author on: Oxford Academic Google Scholar Modern Rheumatology, Volume 26, Issue 5, 2 September 2016, Pages 651–661, https://doi.org/10.3109/14397595.2015.1123349 Published: 02 September 2016 Article history Received: 29 September 2015 Accepted: 18 November 2015 Published: 02 September 2016