医学
GUCY1A3
鸟苷酸环化酶
GUCY1B3
古西亚德
鸟苷酸环化酶2C
内科学
受体
作者
John P. Hanrahan,Albert T. Profy,Bernard J. Lavins,Dennis Ruff,Gabrielle Poirier,James Wakefield,Phebe Wilson,Michael Hall,Mark G. Currie
标识
DOI：10.1016/s0735-1097(16)31285-2
摘要
IW-1973 is an orally active soluble guanylate cyclase (sGC) stimulator that reduces blood pressure (BP) and exhibits anti-fibrotic, anti-inflammatory and organ-protective effects in animal models of systemic hypertension, pulmonary hypertension and heart failure. A Phase 1a first-in-human clinical
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(2025-6-4)
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