13-Methyl-3,4-seco-ent-podocarpanes, rare C18-diterpenoids from the roots of Flueggea virosa

13-Methyl-3,4-seco-ent-podocarpanes from F. virosa were characterized. Their structures were elucidated by extensive spectroscopic analysis. Compound 8 exhibited significant anti-HCV activity with a therapeutic index of 100.5.