Muscle Biopsy: A Practical Approach

Section 1 The Biopsy: Normal and Diseased Muscle 1. The procedure of muscle biopsy 2. Histological and histochemical stains and reactions 3. Normal muscle 4. Definition of pathological changes seen in muscle biopsies 5. Ultrastructural changes in diseased muscle 6. Immunohistochemistry 7. How to read a biopsy Section 2 Pathological Muscle: Individual Diseases 8. Classification of neuromuscular disorders 9. Neurogenic disorders 10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy 11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies 12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies 13. Muscular dystrophies and allied disorders IV: Emeryf{Driefuss muscular dystrophies and Bethlem myopathy 14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy 15. Congenital myopathies 16. Myofibrillar myopathies 17. Metabolic myopathies I: glycogenoses 18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies 19. Endocrine disorders 20. Ion channel disorders 21. Myasthenic syndromes 22. Inflammatory myopathies 23. Toxic and drug-induced myopathies Russell Lane, Charing Cross Hospital Appendix 1. Glossary of commonly used terms References Index