吲唑
催化作用
化学
光催化
可见光谱
组合化学
光化学
功能群
反应条件
有机化学
材料科学
光电子学
聚合物
作者
Sudip Laru,Suvam Bhattacharjee,Alakananda Hajra
摘要
A general and efficient method for visible-light-driven fluoroalkylation, such as difluoromethylphosphonation, difluoroacetamidation, monofluoromethylation, difluoromethylation, and perfluoroalkyalation, of 2H-indazoles using an inexpensive Mn2(CO)10 photocatalyst has been developed. The present methodology affords a new series of C-3 fluoroalkylated 2H-indazole derivatives with wide functional group tolerance in good to excellent yields. Difluoromethylenated indiazoles are also prepared from difluoroester derivatives. Our mechanistic investigations support a radical pathway for the reaction.
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