计算机科学
生物医学中的光声成像
计算机视觉
坐标系
断层摄影术
三维超声
医学影像学
人工智能
超声波
迭代重建
图像质量
医学物理学
生物医学工程
放射科
医学
图像(数学)
光学
物理
作者
Daohuai Jiang,Hongbo Chen,Rui Zheng,Fei Gao
摘要
As an emerging medical diagnostic technology, photoacoustic imaging has been implemented for both preclinical and clinical applications. For clinical convenience, a handheld free-scan photoacoustic tomography (PAT) system providing 3D imaging capability is essentially needed, which has potential for surgical navigation and disease diagnosis. In this paper, we proposed a free-scan 3D PAT (fsPAT) system based on a handheld linear-array ultrasound probe. A global positioning system (GPS) is applied for ultrasound probe's coordinate acquisition. The proposed fsPAT can simultaneously realize real-time 2D imaging and large field-of-view 3D volumetric imaging, which is reconstructed from the multiple 2D images with coordinate information acquired by the GPS. To form a high-quality 3D image, a dedicated space transformation method and a reconstruction algorithm are used and validated by the proposed system. Both simulation and experimental studies have been performed to prove the feasibility of the proposed fsPAT. To explore its clinical potential, in vivo 3D imaging of human wrist vessels is also conducted, showing a clear subcutaneous vessel network with high image contrast.
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