免疫系统
癌症免疫疗法
树突状细胞
免疫疗法
受体
癌细胞
细胞内
化学
细胞生物学
癌症
纳米技术
免疫学
癌症研究
生物
材料科学
生物化学
遗传学
作者
Yeye Hu,Wei Zhang,Xiaozhong Chu,Aoran Wang,Ziliang He,Chuanling Si,Weicheng Hu
标识
DOI:10.1016/j.ijpharm.2023.122703
摘要
Cancer immunity is dependent on dynamic interactions between T cells and dendritic cells (DCs). Polymer-based nanoparticles target DC receptors to improve anticancer immune responses. In this paper, DC surface receptors and their specific coupling natural ligands and antibodies are reviewed and compared. Moreover, reaction mechanisms are described, and the synergistic effects of immune adjuvants are demonstrated. Also, extracellular-targeting antigen-delivery strategies and intracellular stimulus responses are reviewed to promote the rational design of polymer delivery systems.
科研通智能强力驱动
Strongly Powered by AbleSci AI