林奇综合征
医学
内科学
结直肠癌
DNA错配修复
癌症
作者
Adam Daniel Gerrard,Yasuko Maeda,Judith A Strachan,Doug Speake,Malcolm G. Dunlop,Farhat Din
出处
期刊:Diagnostics
[MDPI AG]
日期:2024-10-30
卷期号:14 (21): 2431-2431
标识
DOI:10.3390/diagnostics14212431
摘要
Lynch syndrome (LS) carries a substantial lifetime risk of colorectal cancer which is currently mitigated by biennial colonoscopy surveillance. Paramount to the surveillance programme is the removal of adenomas before malignant transformation but there is an associated service burden and morbidity of repeated endoscopy. We investigated if faecal immunochemical testing (FIT) for faecal haemoglobin has the diagnostic performance to replace colonoscopy.
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