百日咳博德特菌
大环内酯类抗生素
红霉素
微生物学
毒力
百日咳毒素
抗生素
博德杆菌
毒素
生物
细菌
受体
G蛋白
基因
遗传学
作者
Kaichong Jiang,Yang Luan,Wei Wang,Da Xue,S.Y. Tang,Xiaokang Peng,Xiaoguai Liu,Zengguo Wang
出处
期刊:Current Pharmaceutical Biotechnology
[Bentham Science]
日期:2024-09-20
卷期号:26
标识
DOI:10.2174/0113892010320349240905052242
摘要
The macrolide-resistant Bordetella pertussis (MRBp) has appeared in Asia and has even been prevalent in China. Since the antibiotic sensitivity test is not carried out in the clinical setting, macrolide is still the first choice of antibiotic in MRBp infection. Further, the macrolide therapy for pertussis needs to be revised. Macrolide has always shown a positive effect on other macrolide-resistant bacterium infections in clinical applications. However, the mechanism of macrolide on MRBp remains unclear.
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