Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Females and the Elderly: An Update Analysis from the Global Burden of Disease Study 2021

Objective: To update the global burden of Inflammatory Bowel Disease (IBD) using data from the Global Burden of Disease ( GBD ) 2021. Methods: Data from GBD 2021 were analyzed to assess the IBD burden. Results: In 2021, there were 375,140 new cases and 3.83 million total cases of IBD. Elderly-onset IBD accounted for 11% of incidences. 167 countries increased IBD incidence rate, with rates rising in females (APC:+0.06%) and the elderly (APC:+0.14%) but stable in males and the overall population. Conclusion: While the global burden of IBD has decreased overall, it has increased in females and the elderly.