抗氧化剂
紫外线辐射
抑制性突触后电位
化学
紫外线
肽
紫外线照射
生物化学
食品科学
生物
材料科学
物理
放射化学
辐照
光电子学
神经科学
核物理学
作者
Xuchun Zhu,Xiaoyue Zhang,Ziyuan Wang,Feiyue Ren,Xuyou Zhu,Bingyu Chen,Hongzhi Liu,Tana Wuyun
标识
DOI:10.1016/j.foodchem.2024.141336
摘要
In today's social environment, the objective reality of people's increasing life pressure, environmental deterioration, and enhanced ultraviolet rays caused by the destruction of the ozone layer has led to the aggravation of people's oxidative stress. Therefore, exogenous antioxidant peptides have become a hot topic in research. In the context of insufficient protein supply and resource recycling, almond meal was used as raw material in this study. As a by-product of oil processing, it has a protein content of 68 % and antioxidant-related amino acids accounted for 84.62 %, which can be used as a high-quality natural source of antioxidant peptides. Taking antioxidant activity as the only indicator, papain was screened as a hydrolase, and 7 antioxidant peptides such as YLSF, LPSYVN and SPHWNVN were separated and purified. The affinity energy of docking with Keap1-Nrf2-ARE protein molecules was -7.5--8.9 kal/mol, and hydrophobic stacking, hydrogen bonding and intermolecular forces were maintained. Seven antioxidant peptides were synthesized in solid phase, and the IC
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