Efficacy and safety of pulsed field ablation for atrial fibrillation: A systematic review and meta‐analysis

Pacing and Clinical ElectrophysiologyEarly View BRIEF COMMUNICATION Efficacy and safety of pulsed field ablation for atrial fibrillation: A systematic review and meta-analysis Usama Qamar MD, Usama Qamar MD Department of Medicine, King Edward Medical University, Lahore, PakistanSearch for more papers by this authorSiddharth Agarwal MD, Siddharth Agarwal MD orcid.org/0000-0002-5581-5464 Department of Medicine, King Edward Medical University, Lahore, PakistanSearch for more papers by this authorSatyam Krishan MD, Satyam Krishan MD Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USASearch for more papers by this authorAbhishek Deshmukh MD, Abhishek Deshmukh MD Department of Cardiovascular Medicine, Mayo Clinic, Rochester, USASearch for more papers by this authorChristopher V. DeSimone MD, PhD, Christopher V. DeSimone MD, PhD Department of Cardiovascular Medicine, Mayo Clinic, Rochester, USASearch for more papers by this authorStavros Stavrakis MD, PhD, Stavros Stavrakis MD, PhD Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USASearch for more papers by this authorJonathan P. Piccini MD, MHS, Jonathan P. Piccini MD, MHS orcid.org/0000-0003-0772-2404 Department of Cardiovascular Medicine, Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina, USASearch for more papers by this authorZain Ul Abideen Asad MD, MS, Corresponding Author Zain Ul Abideen Asad MD, MS [email protected] [email protected] Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Correspondence Zain Ul Abideen Asad, MD, MS, Assistant Professor of Medicine, Cardiovascular Section, Department of Medicine, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd, AAT 5400, Oklahoma City, OK 73104, USA. Email: [email protected] and [email protected]Search for more papers by this author Usama Qamar MD, Usama Qamar MD Department of Medicine, King Edward Medical University, Lahore, PakistanSearch for more papers by this authorSiddharth Agarwal MD, Siddharth Agarwal MD orcid.org/0000-0002-5581-5464 Department of Medicine, King Edward Medical University, Lahore, PakistanSearch for more papers by this authorSatyam Krishan MD, Satyam Krishan MD Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USASearch for more papers by this authorAbhishek Deshmukh MD, Abhishek Deshmukh MD Department of Cardiovascular Medicine, Mayo Clinic, Rochester, USASearch for more papers by this authorChristopher V. DeSimone MD, PhD, Christopher V. DeSimone MD, PhD Department of Cardiovascular Medicine, Mayo Clinic, Rochester, USASearch for more papers by this authorStavros Stavrakis MD, PhD, Stavros Stavrakis MD, PhD Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USASearch for more papers by this authorJonathan P. Piccini MD, MHS, Jonathan P. Piccini MD, MHS orcid.org/0000-0003-0772-2404 Department of Cardiovascular Medicine, Duke Clinical Research Institute and Duke University Medical Center, Durham, North Carolina, USASearch for more papers by this authorZain Ul Abideen Asad MD, MS, Corresponding Author Zain Ul Abideen Asad MD, MS [email protected] [email protected] Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Correspondence Zain Ul Abideen Asad, MD, MS, Assistant Professor of Medicine, Cardiovascular Section, Department of Medicine, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd, AAT 5400, Oklahoma City, OK 73104, USA. Email: [email protected] and [email protected]Search for more papers by this author First published: 11 February 2024 https://doi.org/10.1111/pace.14947 Usama Qamar and Siddharth Agarwal are the co-primary authors. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat CONFLICT OF INTEREST STATEMENT None of the authors have conflict of interest related to this manuscript. Open Research DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author, upon reasonable request. REFERENCES 1Asad ZUA, Yousif A, Khan MS, et al. Catheter ablation versus medical therapy for atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials. Circ Arrhythm Electrophysiol. 2019; 12:e007414. doi:10.1161/CIRCEP.119.007414 10.1161/CIRCEP.119.007414 PubMedWeb of Science®Google Scholar 2van Driel VJ, Neven K, van Wessel H, et al. Low vulnerability of the right phrenic nerve to electroporation ablation. Heart Rhythm. 2015; 12: 1838-1844. doi:10.1016/j.hrthm.2015.05.012 10.1016/j.hrthm.2015.05.012 PubMedWeb of Science®Google Scholar 3Koruth JS, Kuroki K, Kawamura I, et al. Pulsed field ablation versus radiofrequency ablation: esophageal injury in a novel porcine model. Circ Arrhythm Electrophysiol. 2020; 13:e008303. doi:10.1161/CIRCEP.119.008303 10.1161/CIRCEP.119.008303 PubMedWeb of Science®Google Scholar 4Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021; 372:n71. doi:10.1136/bmj.n71 10.1136/bmj.n71 PubMedGoogle Scholar 5Shaheen N, Shaheen A, Ramadan A, Nashwan AJ. Efficacy and safety of novel pulsed field ablation (PFA) technique for atrial fibrillation: a systematic review and meta-analysis. Health Sci Rep. 2023; 6:e1079. doi:10.1002/hsr2.1079 10.1002/hsr2.1079 PubMedWeb of Science®Google Scholar 6Benali K, Khairy P, Hammache N, et al. Procedure-related complications of catheter ablation for atrial fibrillation. J Am Coll Cardiol. 2023; 81: 2089-2099. doi:10.1016/j.jacc.2023.03.418 10.1016/j.jacc.2023.03.418 PubMedWeb of Science®Google Scholar 7Reddy VY, Gerstenfeld EP, Natale A, et al. Pulsed field or conventional thermal ablation for paroxysmal atrial fibrillation. N Engl J Med. 2023; 389: 1660-1671. doi:10.1056/NEJMoa2307291 10.1056/NEJMoa2307291 CASPubMedGoogle Scholar 8Nault I, Miyazaki S, Forclaz A, et al. Drugs vs. ablation for the treatment of atrial fibrillation: the evidence supporting catheter ablation. Eur Heart J. 2010; 31: 1046-1054. doi:10.1093/eurheartj/ehq079 10.1093/eurheartj/ehq079 PubMedWeb of Science®Google Scholar 9Fortuni F, Casula M, Sanzo A, et al. Meta-analysis comparing cryoballoon versus radiofrequency as first ablation procedure for atrial fibrillation. Am J Cardiol. 2020; 125: 1170-1179. doi:10.1016/j.amjcard.2020.01.016 10.1016/j.amjcard.2020.01.016 PubMedWeb of Science®Google Scholar 10Turagam MK, Neuzil P, Schmidt B, et al. Safety and effectiveness of pulsed field ablation to treat atrial fibrillation: one-year outcomes from the MANIFEST-PF registry. Circulation. 2023; 148: 35-46. doi:10.1161/CIRCULATIONAHA.123.064959 10.1161/CIRCULATIONAHA.123.064959 CASPubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation